Table 3 Significance of the SNP ABCB1 C3435T gene
CC | CT | TT | p Value | |
|---|---|---|---|---|
Age | ||||
≤ 60 | 21 | 44 | 28 | |
> 60 | 10 | 20 | 12 | .979 |
Gener | ||||
Female | 13 | 28 | 24 | |
Male | 18 | 36 | 16 | .199 |
Blast count | ||||
< 40 | 10 | 20 | 15 | |
40–60 | 6 | 15 | 3 | |
> 60 | 15 | 29 | 22 | .361 |
WBC count, 109/L (range) | ||||
< 35 | 14 | 40 | 30 | |
35–100 | 12 | 14 | 5 | |
> 100 | 5 | 10 | 5 | .092 |
Immunophenotype | ||||
M1 | 0 | 2 | 2 | |
M2 | 10 | 18 | 14 | |
M4 | 20 | 38 | 23 | |
M5 | 1 | 1 | 0 | |
M6 | 0 | 3 | 1 | |
M7 | 0 | 2 | 0 | .719 |
Cytogenetics | ||||
Unsuccessful karyotype | 18 | 26 | 19 | |
Normal karyotype | 12 | 37 | 19 | |
Abnormal karyotype | 1 | 1 | 2 | .411 |
Response | ||||
Response complete | 12 | 26 | 17 | |
Remission partial | 6 | 5 | 5 | |
Refractory disease | 3 | 15 | 10 | |
Death in aplasia | 7 | 15 | 8 | |
Death by undetermined cause | 3 | 3 | 0 | .372 |