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Table 9 SNP–SNP interaction models analyzed by the MDR method

From: CTNNA3 genetic polymorphism may be a new genetic signal of type 2 diabetes in the Chinese Han population: a case control study

Model

Training Bal. Acc

Testing Bal. Acc

OR (95% CI)

p value

CVC

rs7914287

0.537

0.520

1.35 (1.05–1.73)

0.0191

9/10

rs7920624, rs2441727

0.557

0.541

1.58 (1.23–2.04)

0.0003

9/10

rs7920624, rs2441727, rs7914287

0.582

0.525

1.96 (1.52–2.54)

 < 0.0001

9/10

rs10822745, rs7920624, rs2441727, rs7914287

0.607

0.543

2.41 (1.86–3.12)

 < 0.0001

10/10

  1. MDR, multifactor dimensionality reduction; Bal. Acc., balanced accuracy; CVC, cross-validation consistency; OR, odds ratio; 95% CI, 95% confidence interval
  2. p values were calculated using χ2 tests; p < 0.05 and bold text indicate statistical significance
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BMC Medical Genomics

ISSN: 1755-8794

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