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Table 9 SNP–SNP interaction models analyzed by the MDR method

From: CTNNA3 genetic polymorphism may be a new genetic signal of type 2 diabetes in the Chinese Han population: a case control study

Model Training Bal. Acc Testing Bal. Acc OR (95% CI) p value CVC
rs7914287 0.537 0.520 1.35 (1.05–1.73) 0.0191 9/10
rs7920624, rs2441727 0.557 0.541 1.58 (1.23–2.04) 0.0003 9/10
rs7920624, rs2441727, rs7914287 0.582 0.525 1.96 (1.52–2.54)  < 0.0001 9/10
rs10822745, rs7920624, rs2441727, rs7914287 0.607 0.543 2.41 (1.86–3.12)  < 0.0001 10/10
  1. MDR, multifactor dimensionality reduction; Bal. Acc., balanced accuracy; CVC, cross-validation consistency; OR, odds ratio; 95% CI, 95% confidence interval
  2. p values were calculated using χ2 tests; p < 0.05 and bold text indicate statistical significance