Parameters | PPARD rs2016520 | P values | ||
---|---|---|---|---|
 | TT | TC + CC | ||
N (male/femal) | Â | 35(24/11) | 25(15/10) | 0.493b |
FPG (mmol/L) | Before | 9.07 ± 2.63 | 8.19 ± 1.42 | 0.134 |
After | 6.74 ± 1.36 | 6.57 ± 0.87222 | 0.579 | |
DV |  − 2.32 ± 1.72 |  − 1.61 ± 1.44 | 0.099 | |
PPG (mmol/L) | Before | 15.23 ± 2.78 | 12.90 ± 2.66 | 0.002 |
After | 10.57 ± 1.71 | 10.31 ± 1.42 | 0.538 | |
DV |  − 4.66 ± 2.70 |  − 2.59 ± 2.13 | 0.002 | |
FINS (mU/L) | Before | 9.36 ± 5.93 | 9.13 ± 5.91 | 0.883 |
After | 16.06 ± 15.72 | 11.32 ± 9.05 | 0.182 | |
DV | 6.70 ± 15.03 | 2.19 ± 10.33 | 0.201 | |
PINS (mU/L) | Before | 41.55 ± 30.72 | 36.23 ± 36.61 | 0.544 |
After | 75.14 ± 54.71 | 63.29 ± 50.51 | 0.397 | |
DV | 33.59 ± 43.71 | 27.07 ± 29.25 | 0.519 | |
HOMA-IR | Before | 3.81 ± 2.65 | 2.72 ± 1.47 | 0.443 |
After | 4.94 ± 4.94 | 3.34 ± 2.97 | 0.157 | |
DV | 1.12 ± 4.85 |  − 0.01 ± 3.53 | 0.338 | |
HOMA-B | Before | 28.25 ± 16.60 | 25.22 ± 14.80 | 0.469 |
After | 73.20 ± 42.81 | 50.74 ± 26.43 | 0.015 | |
DV | 44.95 ± 19.23 | 25.48 ± 15.93 | 0.000 | |
HbA1c (%) | Before | 8.58 ± 1.81 | 7.02 ± 1.60 | 0.221 |
After | 6.58 ± 1.12 | 6.42 ± 0.80 | 0.543 | |
DV |  − 1.87 ± 1.55 |  − 1.60 ± 1.44 | 0.714 | |
TG (mmol/L) | Before | 2.19 ± 1.58 | 2.09 ± 0.92 | 0.782 |
After | 1.90 ± 1.26 | 1.78 ± 0.83 | 0.690 | |
DV |  − 0.29 ± 0.78 |  − 0.31 ± 0.64 | 0.926 | |
TC (mmol/L) | Before | 4.67 ± 1.20 | 4.45 ± 0.88 | 0.906 |
After | 4.74 ± 1.19 | 4.52 ± 0.87 | 0.439 | |
DV |  − 0.29 ± 0.75 |  − 0.55 ± 1.12 | 0.283 | |
HDL-C (mmol/L) | Before | 1.29 ± 0.45 | 1.31 ± 0.38 | 0.788 |
After | 1.38 ± 0.41 | 1.64 ± 0.92 | 0.158 | |
DV | 0.09 ± 0.38 | 0.32 ± 0.87 | 0.183 | |
LDL-C (mmol/L) | Before | 2.79 ± 0.80 | 2.87 ± 0.78 | 0.720 |
After | 2.75 ± 0.79 | 2.58 ± 0.67 | 0.364 | |
DV |  − 0.04 ± 0.61 | 0.29 ± 0.57 | 0.110 |