From: Mutational signatures among young-onset testicular cancers
Signature | 20–29 | 30–39 | > 40 | p-value (20–29 vs. > 40) | p-value (30–39 vs. > 40) | p-value (continuous age) |
---|---|---|---|---|---|---|
Signature 1 | 16 (40%) | 16 (39%) | 2 (10%) | 0.12 | 0.047* | 0.14 |
Signature 3 | 35 (88%) | 34 (83%) | 18 (90%) | 0.69 | 0.41 | 0.54 |
Signature 6 | 17 (42%) | 13 (32%) | 10 (50%) | 0.40 | 0.15 | 0.55 |
Signature 8 | 14 (35%) | 14 (34%) | 0 (0%) | NA | NA | 0.020* |
Signature 11 | 3 (8%) | 2 (5%) | 6 (30%) | 0.10 | 0.026* | 0.010* |
Signature 13 | 5 (12%) | 6 (15%) | 3 (15%) | 0.64 | 0.73 | 0.29 |
Signature 15 | 11 (28%) | 11 (27%) | 5 (25%) | 0.43 | 0.78 | 0.51 |
Signature 16 | 16 (40%) | 16 (39%) | 14 (70%) | 0.034* | 0.032* | 0.13 |
Signature 19 | 12 (30%) | 17 (41%) | 5 (25%) | 0.85 | 0.23 | 0.80 |
Signature 20 | 6 (15%) | 8 (20%) | 3 (15%) | 0.83 | 0.73 | 0.90 |
Signature 24 | 21 (52%) | 17 (41%) | 9 (45%) | 0.69 | 0.80 | 0.55 |
Signature 26 | 2 (5%) | 6 (15%) | 4 (20%) | 0.22 | 0.84 | 0.49 |
Signature 29 | 14 (35%) | 12 (29%) | 2 (10%) | 0.039* | 0.085 | 0.036* |
Signature 30 | 28 (70%) | 23 (56%) | 10 (50%) | 0.23 | 0.82 | 0.32 |