Association of single nucleotide polymorphisms with insulin secretion, insulin sensitivity, and diabetes in women with a history of gestational diabetes mellitus

Table 5 SNPs with nominal p-values for association with diabetes up to 5 years after a pregnancy complicated by GDM

SNP	Gene/nearest gene	Location	CHR	RA/OA	OR (CI)	p value	p value (FDR_BH)
rs4607103	ADAMTS9-AS2	Intron	3	C/T	0.47 (0.30–0.73)	0.00055	0.039
rs4607517	GCK	Intergenic	7	A/G	1.765 (1.09–2.85)	0.019	0.4902
rs1552224	CENTD2	Intergenic	11	A/C	2.22 (1.09–4.61)	0.024	0.4902
rs11634397	ZFAND6	Intergenic	15	G/A	1.58 (1.03–2.42)	0.037	0.4902
rs7578597	THADA	Coding—missense	2	T/C	3.29 (1.004–10.75)	0.037	0.4902
rs4457053	ZBED3	Intron of ZBED3-AS1	5	G/A	1.56 (1.02–2.38)	0.041	0.4902

SNP = single nucleotide polymorphism, CHR = chromosome, SNP = single nucleotide polymorphisms, RA/OA = risk allele/other allele, OR = estimated odds ratio (for risk), P value = nominal p-value for this test, FDR_BH = Benjamini & Hochberg (1995) step-up FDR control

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