Skip to main content

Table 5 SNPs with nominal p-values for association with diabetes up to 5 years after a pregnancy complicated by GDM

From: Association of single nucleotide polymorphisms with insulin secretion, insulin sensitivity, and diabetes in women with a history of gestational diabetes mellitus

SNP Gene/nearest gene Location CHR RA/OA OR (CI) p value p value (FDR_BH)
rs4607103 ADAMTS9-AS2 Intron 3 C/T 0.47
(0.30–0.73)
0.00055 0.039
rs4607517 GCK Intergenic 7 A/G 1.765
(1.09–2.85)
0.019 0.4902
rs1552224 CENTD2 Intergenic 11 A/C 2.22
(1.09–4.61)
0.024 0.4902
rs11634397 ZFAND6 Intergenic 15 G/A 1.58
(1.03–2.42)
0.037 0.4902
rs7578597 THADA Coding—missense 2 T/C 3.29
(1.004–10.75)
0.037 0.4902
rs4457053 ZBED3 Intron of ZBED3-AS1 5 G/A 1.56
(1.02–2.38)
0.041 0.4902
  1. SNP = single nucleotide polymorphism, CHR = chromosome, SNP = single nucleotide polymorphisms, RA/OA = risk allele/other allele, OR = estimated odds ratio (for risk), P value = nominal p-value for this test, FDR_BH = Benjamini & Hochberg (1995) step-up FDR control