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Table 2 IVW multivariable MR for the effects of TGs on COVID-19 risk adjusted for other traits

From: Estimating causal effects of atherogenic lipid-related traits on COVID-19 susceptibility and severity using a two-sample Mendelian randomization approach

Exposure traits Adjustment Outcome traits
COVID-19 susceptibility COVID-19 hospitalization COVID-19 severity
OR (95% CI), P-value OR (95% CI), P-value OR (95% CI), P-value
Apo-B TG 0.966 (0.89–1.05), 0.422 0.905 (0.77–1.06), 0.228 0.954 (0.73–1.24), 0.725
TG Apo-B 1.063 (0.98–1.15), 0.139 1.178 (1.01–1.37), 0.036 1.306 (1.06–1.60), 0.011
LDL TG 1.017 (0.93–1.12), 0.717 0.948 (0.79–1.13), 0.558 1.036 (0.79–1.35), 0.795
TG LDL-C 1.073 (0.99–1.16), 0.073 1.158 (1.00–1.34), 0.042 1.276 (1.05–1.55), 0.013
BMI TG 1.130 (1.02–1.25), 0.016 1.374 (1.13–1.67), 0.001 1.404 (1.08–1.83), 0.012
TG BMI 1.071 (0.99–1.15), 0.066 1.189 (1.04–1.36), 0.013 1.261 (1.04–1.53), 0.018
  1. Apo-B, apolipoprotein B; BMI, body mass index; CI, confidence interval; COVID-19, coronavirus disease 2019; IVW, inverse variance weighted; LDL-C, low-density lipoprotein cholesterol; MR, Mendelian randomization; OR, odds ratio; SE, standard error; SNV, single nucleotide variant; TG, triglyceride