Table 3 The top three significant modules and hub genes in the PPI network
Plug-in | Modules | Nodes | Edges | Genes |
|---|---|---|---|---|
MCODE | Module 1 | 15 | 89 | RAC2, FERMT3, ARHGAP9, LSP1, CORO1A, GMFG, TYROBP, LAPTM, CD52, CD48, NCF4, LCP1, ARHGDIB, HCLS1, APBB1IP |
MCODE | Module 2 | 5 | 9 | C1QA, CCR5, ALOX5AP, MPEG1, AIF1 |
MCODE | Module 3 | 5 | 9 | DOK2, INPP5D, JAK3, SYK, PTK2B |
CytoHubba | Hub gene | 10 | 45 | LAPTM5, LCP1, HCLS1, CORO1A, CD48, TYROBP, RAC2, ARHGDIB, FERMT3, NCF4 |