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Fig. 3 | BMC Medical Genomics

Fig. 3

From: Transcriptome sequencing reveals a lncRNA–mRNA interaction network in extramammary Paget’s disease

Fig. 3

GO and KEGG analyses of the differentially expressed mRNAs. A GO annotation of the differentially expressed mRNAs. The bar plot presents the enrichment scores (− log10 [p value]) of the top 10 significantly enriched GO terms in biological processes, cellular components and molecular functions (top); the Z score was calculated to reflect the general expression trend of the DE mRNAs contained in each GO term (bottom). B Bulb map of KEGG analysis for the differentially expressed mRNAs (top). The X-axis indicates the enrichment score of differentially expressed genes. Y-axis lists the names of enriched pathways. The size of the node represents the number of enriched differential genes. The P value is represented by a color scale, where the statistical significance increases as purple turns to red. (Bottom) Heatmap for the log2FC of DE mRNAs contained in the significantly enriched KEGG pathways

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