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Fig. 2 | BMC Medical Genomics

Fig. 2

From: Modular signature of long non-coding RNA association networks as a prognostic biomarker in lung cancer

Fig. 2

Identification of correlated lncRNA-mRNA pairs and associated lncRNAs. A The distribution of the SCCs of lncRNA-mRNA pairs. B The distribution of the number of correlated mRNAs per lncRNA. The lncRNA-positively correlated mRNAs are defined as top 0.1% of mutual rank index (yellow) of lncRNA-mRNA pairs; the lncRNA-negatively correlated mRNAs are defined as bottom 0.1% of mutual rank index (blue) of lncRNA-mRNA pairs. C The PCC between each lncRNA was calculated considering the number of their correlated mRNAs. The distribution of PCC according to the lncRNA-positively correlated mRNAs (blue) and lncRNA-negatively correlated mRNAs (yellow) were plotted. N, measurement according to lncRNA-negatively correlated mRNAs; P, measurement according to lncRNA-positively correlated mRNAs; SCC, spearman’s rank correlation coefficient

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BMC Medical Genomics

ISSN: 1755-8794

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