Table 2 Basic information of SNPs in IL-6 gene
From: An intron SNP rs2069837 in IL-6 is associated with osteonecrosis of the femoral head development
SNP | Chr: position | Function | Allele (minor/major) | MAF in Case | MAF in Control | O (HET) | E (HET) | HWE p | HaploReg |
|---|---|---|---|---|---|---|---|---|---|
rs2069837 | 7: 22728408 | Intronic | G/A | 0.183 | 0.227 | 0.356 | 0.351 | 0.905 | Promoter histone marks; Enhancer histone marks; DNAse; Proteins bound; Motifs changed |
rs13306435 | 7: 22731420 | Missense | A/T | 0.034 | 0.038 | 0.072 | 0.073 | 0.564 | Promoter histone marks; Enhancer histone marks; DNAse; Motifs changed |