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Fig. 4 | BMC Medical Genomics

Fig. 4

From: A genomic mutation spectrum of collecting duct carcinoma in the Chinese population

Fig. 4

The CDKN2A-mediated p53/RB1 pathway is mostly altered in the CDC population. A Comparison of pathway-level alterations across the CDC, BLCA, KIRC and KIRP cohorts considering single-nucleotide variants (SNVs). B Comparison of pathway-level alterations across the CDC, BLCA, KIRC and KIRP cohorts considering copy number variants (CNVs). C SNVs and CNVs in components of the p53/RB1 pathway among the CDC, KIRC, KIRP and BLCA cohorts (from left to right in the box). Red, oncogene alterations; blue, tumour suppressor alterations. Percentages denote altered fractions. KIRC, clear cell renal cell carcinoma; KIRP, papillary renal cell carcinoma; BLCA, bladder carcinoma; CDC, collecting duct carcinoma

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