Table 2 Baseline characteristics of patients (cases) and healthy (control) groups and tumor features
From: Association of SMAD7 genetic markers and haplotypes with colorectal cancer risk
Characteristic | Cases | Controls | p-value | OR (95%CI) |
|---|---|---|---|---|
Gender | ||||
Female | 95(45.5%) | 100(50%) | Ref | |
Male | 114(54.5%) | 100(50%) | 0.358 | 0.83 (0.56–1.23) |
Age of diagnosisa (year) | 56.84 ± 13.6 | 57.35 ± 8.4 | 0.192 | 0.99 (0.97–1.01) |
Smoking status | ||||
Positive | 19(9.0%) | 29(14.5%) | Ref | |
Negative | 156(74.6%) | 171(85.5%) | 0.179 | 0.65 (0.35–1.21) |
Family history | ||||
Positive | 35(16.7%) | 40(20.0%) | Ref | |
Negative | 131(62.6%) | 160(80.0%) | 0.321 | 0.78 (0.48–1.27) |
BMI (Kg/m2)b | 25.5 ± 4.8 | 27.8 ± 4.9 | < 0.001 | 0.90 (0.86–0.95) |
Tumor location | ||||
Rectum | 75 (35.8) | |||
Colon | 59 (28.2) | |||
Sigmoid | 43 (20.5) | |||
Grade | ||||
Poor | 65 (31.1) | |||
Moderate | 89 (42.5) | |||
Well | 23 (11.0) |