Table 5 Stratified analyses between TP73 gene rs1801173 polymorphism and risk by sex, age, smoking status and alcohol consumption
Variable | (Case/control) | Adjusted OR (95% CI); P | ||||||
|---|---|---|---|---|---|---|---|---|
CC | TC | TT | CC | TC | TT | (TC + TT) versus CC | TT versus (CC + TC) | |
Sex | ||||||||
Male | 229/253 | 131/168 | 22/23 | 1.00 | 0.86 (0.65–1.15); P:0.314 | 1.06 (0.57–1.95); P:0.859 | 0.89 (0.67–1.17); P:0.389 | 0.89 (0.49–1.63); P:0.715 |
Female | 112/143 | 59/65 | 9/13 | 1.00 | 1.16 (0.75–1.78); P:0.502 | 0.88 (0.37–2.14); P:0.785 | 1.11 (0.74–1.68); P:0.607 | 0.84 (0.35–2.02); P:0.700 |
Age | ||||||||
< 62 | 163/182 | 90/117 | 8/16 | 1.00 | 0.86 (0.61–1.22); P:0.390 | 0.56 (0.23–1.34); P:0.186 | 0.82 (0.59–1.15); P:0.255 | 1.69 (0.71–4.02); P:0.228 |
≥ 62 | 178/214 | 100/116 | 23/20 | 1.00 | 1.04 (0.74–1.45); P:0.833 | 1.38 (0.74–2.60); P:0.313 | 1.09 (0.79–1.49); P:0.602 | 0.73 (0.39–1.36); P:0.324 |
Smoking status | ||||||||
Never | 228/290 | 119/172 | 21/24 | 1.00 | 0.87 (0.65–1.16); P:0.331 | 1.11 (0.60–2.05); P:0.731 | 0.91 (0.69–1.20); P:0.498 | 0.86 (0.47–1.57); P:0.619 |
Ever | 113/106 | 71/61 | 10/12 | 1.00 | 1.09 (0.71–1.68); P:0.691 | 0.78 (0.32–1.89); P:0.583 | 1.04 (0.69–1.57); P:0.849 | 1.32 (0.56–3.14); P:0.526 |
Alcohol consumption | ||||||||
Never | 273/305 | 144/180 | 23/28 | 1.00 | 0.89 (0.68–1.18); P:0.420 | 0.68 (0.39–1.16); P:0.156 | 0.90 (0.69–1.17); P:0.414 | 1.42 (0.83–2.42); P:0.196 |
Ever | 68/91 | 46/53 | 8/8 | 1.00 | 1.16 (0.70–1.92); P:0.561 | 1.34 (0.48–3.75); P:0.578 | 1.19 (0.73–1.92); P:0.491 | 0.79 (0.29–2.17); P:0.650 |