Fig. 6

FISH study with an ETV6 (12p13) break apart probe for Case 2 (A) and the specimen from the 4th recurrence of Case 3 (B). The yellow signal (red/green fusion, arrow head) demonstrates an intact chromosome, whereas a separated red (big arrow) and green signals (small arrow) indicate a break in the ETV6 gene. (A) Fig. 3D adapted from Suzuki et al. 2017 [22]. Permission was obtained from Karger AG. Scale bars, 25 µm (A); 10 µm (B)