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Fig. 8 | BMC Medical Genomics

Fig. 8

From: A novel prognostic model for hepatocellular carcinoma based on 5 microRNAs related to vascular invasion

Fig. 8

Construction of the VI-related miRNA-mRNA regulatory network. (a) The soft threshold determination was based on scale-free topology criterion. (b) Modules with different colors were assigned by the Dynamic Tree Cut algorithm. (c) Heatmap showed the correlation between VI and the characteristic gene value of the module. Values outside of brackets are correlation coefficients, and values inside of brackets were gene significance level. (d) Scatterplot showed a highly significant correlation between gene significance for VI versus module membership in the salmon module. (e) The miRNA-mRNA network related to VI in HCC patients. Light blue diamonds represented mRNAs; purple ellipses represented miRNAs. (f) Protein–protein interactions illustrated the relationships between proteins

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