Fig. 6

Gene set enrichment analysis (GSEA) with two-risk group. a–c The top 3 gene sets enriched in the high-risk group included the cell cycle (NES = 2.31, Norm P < 0.001, FDR q = 0.003), pyrimidine metabolism (NES = 2.26, Norm P < 0.001, FDR q = 0.003), RNA degradation (NES = 2.23, Norm P < 0.001, FDR q = 0.002); d–f The top 3 gene sets enriched in the low-risk group included asthma (NES = − 2.05, Norm P < 0.001, FDR q = 0.041), intestinal immune network for IgA production (NES = − 2.01, Norm P = 0.004, FDR q = 0.034) and hematopoietic cell lineage (NES = − 1.95, Norm P < 0.001, FDR q = 0.047)