Table 2 Univariate and multivariate Cox regression analysis

Training cohort

 Age

1.013 (0.990–1.036)

0.261

1.032 (1.007–1.057)

0.011

 Sex

1.444 (0.935–2.228)

0.097

1.317 (0.849–2.043)

0.218

 Stage

1.763 (1.431–2.171)

 < 0.001

1.803 (1.435–2.266)

 < 0.001

 Risk score

2.405 (1.952–2.964)

 < 0.001

2.444 (1.964–3.040)

 < 0.001

Test cohort

 Age

1.004 (0.983–1.024)

0.734

1.005 (0.985–1.025)

0.631

 Sex

0.867 (0.575–1.308)

0.497

0.837 (0.544–1.287)

0.417

 Stage

1.526 (1.265–1.842)

 < 0.001

1.557 (1.285–1.887)

 < 0.001

 Risk score

1.718 (1.435–2.056)

 < 0.001

1.734 (1.438–2.093)

 < 0.001