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Table 2 HWE test of genotypes in 146 patients

From: Relationship of cytochrome P450 gene polymorphisms with blood concentrations of hydroxychloroquine and its metabolites and adverse drug reactions

Polymorphism SNP HWE P-value Polymorphism SNP HWE P-value
CYP 2C8 rs2071426 0.23758 CYP3A4 rs28371759 0.93359
  rs17110453 0.09269   rs4646440 0.29517
  rs1341159 0.04798*   rs4646437 0.75722
  rs1557044 0.18561   rs3735451 0.85980
  rs10882526 0.69981   rs2246709 0.54361
  rs6583969 0.39241   rs2242480 0.12091
  rs11572139 0.40038 CYP2D6 rs28371699 0.00160*
  rs7909236 0.34911   rs4078247 0.00947*
  rs2185571 0.40038   rs28670611 0.00235*
  rs1934952 0.25790   rs1080983 0.00144*
  rs11572162 0.54993   rs35028622 0.00147*
  rs1058932 0.79740   rs5758589 0.07308
CYP3A5 rs1419745 0.91067    
  rs4646450 0.95620    
  rs15524 0.61950    
  rs776746 0.77629    
  rs3800959 0.43860    
  1. *P < 0.05, indicates no genetic mutation and no statistical analysis is needed