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Fig. 4 | BMC Medical Genomics

Fig. 4

From: A novel defined risk signature based on pyroptosis-related genes can predict the prognosis of prostate cancer

Fig. 4

Eight genes-based prognostic signature was constructed using Lasso-Cox regression analysis, and its efficacy was tested. A The distribution of partial likelihood deviation of Lasso coefficient preserves 15 variables when partial likelihood deviation reaches the minimum (Log Lambda = − 3.45). PFS risk profile for risk score-based patients in TCGA cohort (increased number of patients with biochemical relapse (BCR) as scores increased) (B), K–M surviving curve (log-rank test, p < 0.001) (C). PFS risk profile for risk score-based patients in GSE70769 cohort (same as TCGA cohort, with increased incidence of BCR as scores increased) (D), K–M survival curve (log-rank test, p < 0.001) (E). Overall survival risk profile for risk score-based patients in TCGA cohort (increased number of patients die as the score increases) (F), K–M survivable curve (log-rank test, p = 0.02) (G)

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