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Fig. 1 | BMC Medical Genomics

Fig. 1

From: Characterization of a novel HLA-A*11:335 allele resulting from a rare interlocus recombination involving HLA-A*11:01:01:01/126 and HLA-H*02:07/14/18 alleles with nanopore sequencing, in a volunteer from the China Marrow Donor Program

Fig. 1

A Comparison of the exon 4 nucleotide sequence of HLA-A*11:126 and HLA-A*11:01:01:01. The numbers above the sequence indicate the cDNA position. Identity between sequences is indicated by dashes. The difference between sequences is highlighted by an arrowhead, which was the only difference between the two alleles. B A genotype analysis of HLA-A using the GENDX software program. The recommended genotype was A*01:01:01:01/A*11:126; however, numerous mismatches between exon 4 and exon 6 were observed (indicated by triangles). The purple vertical line insertion mark indicates an “AT” deletion in intron 5 in the A*11 allele. The yellow blocks indicate exon 1 ~ 8. The white blocks after each exon indicate the corresponding intron (1 ~ 7). The numbers below the yellow and white blocks indicate the position of gDNA (from 1 to 3000)

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