|
Traits
|
Data sources
|
Sample size (cases/controls)
|
Ancestry
|
Use
|
|---|
|
OSA
|
FinnGen [12]
|
16,761/201,194
|
European
|
Exposure/Outcome
|
|
AF
|
Nielsen et al. [13]
|
60,620/970,216
|
European
|
Exposure/Outcome
|
|
AF
|
AF HRC [14]
|
65,446/522,744
|
Mixed (84.2% European)
|
Outcome for replication analyses
|
|
Snoring
|
UK Biobank [15]
|
152,302/256,015
|
European
|
Additional analyses
|
|
Body mass index
|
Hoffmann et al. [16]
|
334,487
|
Mixed (94.3% European)
|
Confounder for MVMR analyses
|
|
HTN, SBP, DBP
|
Neale laboratory [17]
|
317,754
|
European
|
Confounder for MVMR analyses
|
|
Type 2 diabetes
|
Mahajan et al. [18]
|
74,124/824,006
|
European
|
Confounder for MVMR analyses
|
|
LDL-C, HDL-C, TG
|
Richardson et al. [19]
|
403,943 ~ 441,016
|
European
|
Confounder for MVMR analyses
|
- OSA, obstructive sleep apnea; AF, atrial fibrillation; MVMR, multivariable Mendelian randomization; HTN, hypertension; SBP, systolic blood pressure; DBP, diastolic blood pressure; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TG, triglycerides; AF HRC, Atrial Fibrillation Haplotype Reference Consortium
