Table 1 Characteristics of data sources used in the Mendelian randomization study
Traits | Data sources | Sample size (cases/controls) | Ancestry | Use |
|---|---|---|---|---|
OSA | FinnGen [12] | 16,761/201,194 | European | Exposure/Outcome |
AF | Nielsen et al. [13] | 60,620/970,216 | European | Exposure/Outcome |
AF | AF HRC [14] | 65,446/522,744 | Mixed (84.2% European) | Outcome for replication analyses |
Snoring | UK Biobank [15] | 152,302/256,015 | European | Additional analyses |
Body mass index | Hoffmann et al. [16] | 334,487 | Mixed (94.3% European) | Confounder for MVMR analyses |
HTN, SBP, DBP | Neale laboratory [17] | 317,754 | European | Confounder for MVMR analyses |
Type 2 diabetes | Mahajan et al. [18] | 74,124/824,006 | European | Confounder for MVMR analyses |
LDL-C, HDL-C, TG | Richardson et al. [19] | 403,943 ~ 441,016 | European | Confounder for MVMR analyses |