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Fig. 1 | BMC Medical Genomics

Fig. 1

From: Machine learning and bioinformatics analysis revealed classification and potential treatment strategy in stage 3–4 NSCLC patients

Fig. 1

Unsupervised clustering of TIICS in stage 3–4 NSCLC. A. Top: Consensus clustering of the pairwise correlation of TIICs. Three modules associations were indicated in the heatmap. Middle: Five representative immune cells (T cells CD8, M1.Macrophage, Monocyte, M2.Macrophage, M0.Macrophage) from each module, with heatmap indicating the abundance (Dark colour represents high expression level, while the light colour represents the low expression level). Bottom: Distribution of the five selected TIICs within the three clusters (row), with dashed line indicating the median. B Radar graph indicates the ESTIMATE scores and four immunotherapy-related signature scores in three clusters. Line color represents the three clusters: Red for cluster-1, green for cluster-2, and blue for cluster-3

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