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Table 2 Results of reanalysis of MDA products with next-generation sequencing

From: Comparison of chromosomal status in reserved multiple displacement amplification products of embryos that resulted in miscarriages or live births: a blinded, nonselection case–control study

NGS results Miscarriage cases (n = 28) Live birth controls (n = 56) P valuea OR (95%CI)
Euploid 13 (46.4) 48 (85.7) < 0.001 0.327 (0.185–0.576)
Whole-chromosome aneuploid 7 (25.0) 0 < 0.001  
Mosaic 5 (17.9) 5 (8.9) 0.404 1.378 (0.728–2.610)
Segmental abnormality 3 (10.7) 2 (3.6) 0.327 1.709 (0.578–5.052)
Chaotic 0 1 (1.8) 0.003  
  1. Values are presented as n (%)
  2. MDA multiple displacement amplification, NGS next-generation sequencing
  3. aFisher's exact test