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Fig. 4 | BMC Medical Genomics

Fig. 4

From: Comparison of tumor and two types of paratumoral tissues highlighted epigenetic regulation of transcription during field cancerization in non-small cell lung cancer

Fig. 4

Field cancerization (FC)-specific differentially methylated regions (DMRs). A DMRs with methylation level: tumor-distant normal tissues < tumor-adjacent normal tissues < tumor tissues; B DMRs with methylation level: tumor-distant normal tissues > tumor-adjacent normal tissues > tumor tissues; C The overlap of FC-specific DMRs with tumor-specific DMRs; D Enrichment of transcriptional factors in genes differentially methylated in tumor-adjacent normal tissues

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