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Fig. 5 | BMC Medical Genomics

Fig. 5

From: Comparison of tumor and two types of paratumoral tissues highlighted epigenetic regulation of transcription during field cancerization in non-small cell lung cancer

Fig. 5

Association between DNA methylation levels of field cancerization-specific differentially methylated regions (DMRs) and clinicohistologic characteristics. (A) Relative DNA methylation levels per histology among hypermethylated DMRs. (B) Correlation between relative DNA methylation evels and tumor size or (C) patient age among hypermethylated DMRs. (D) Relative DNA methylation levels per sex among hypomethylated DMRs. Hypermethylated DMRs refer to those showing a methylation level pattern of tumor-distant normal tissues < tumor-adjacent normal tissues < tumor tissues, and hypomethylated DMRs refer to those with a complete reversed pattern. ADC adenocarcinoma, SCC squamous cell carcinoma

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BMC Medical Genomics

ISSN: 1755-8794

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