|
Characteristic
|
No. of patients (%)
|
|---|
|
Age, years (Median [Range])
|
58.6 [30–73]
|
|
Sex
|
|
Male
|
19 (52.8)
|
|
Female
|
17 (47.2)
|
|
Smoking status
|
|
Never
|
16 (44.4)
|
|
Former
|
6 (16.7)
|
|
Current
|
14 (38.9)
|
|
Tumor size (cm2)
|
|
< 5
|
10 (27.8)
|
|
5–9
|
12 (33.3)
|
|
10–20
|
11 (30.6)
|
|
> 20
|
3 (8.3)
|
|
Histology
|
|
ADC
|
18 (50.0)
|
|
SCC
|
7 (19.4)
|
|
Others
|
11 (30.6)
|
|
T stage
|
|
T1
|
12 (33.3)
|
|
T2
|
11 (30.6)
|
|
T3
|
6 (16.7)
|
|
T4
|
6 (16.7)
|
|
Unknown
|
1 (2.8)
|
|
N stage
|
|
N0
|
22 (61.1)
|
|
N1
|
10 (27.8)
|
|
N2
|
3 (8.3)
|
|
Unknown
|
1 (2.8)
|
- The 52 enrolled patients underwent exclusion by tumor cell fraction within their TUM, ADJ, and DIS samples, and 36 were eligible for subsequent analyses. ADJ—tumor-adjacent normal tissue. DIS—tumor-distant normal tissue. TUM—surgically-resected tumor
