Variables | Whole-cohort AML | Non-M3 AML | CN-AML | |||
---|---|---|---|---|---|---|
HR (95% CI) | P | HR (95% CI) | P | HR (95% CI) | P | |
SPAG1 expression | 2.280 (1.562–3.327) | 0.000 | 2.011 (1.366–2.962) | 0.000 | 2.279 (1.283–4.047) | 0.005 |
SPAG2/UAP1 expression | 1.313 (0.908–1.897) | 0.148 | 1.536 (1.052–2.241) | 0.026 | 1.051 (0.614–1.798) | 0.857 |
SPAG3/SPAG8 expression | 0.901 (0.624–1.302) | 0.578 | 1.021 (0.699–1.490) | 0.914 | 0.801 (0.469–1.367) | 0.416 |
SPAG4 expression | 0.881 (0.610–1.273) | 0.501 | 1.047 (0.718–1.527) | 0.812 | 0.762 (0.442–1.315 | 0.329 |
SPAG5 expression | 0.845 (0.584–1.223) | 0.373 | 0.747 (0.509–1.096) | 0.136 | 0.564 (0.319–0.998) | 0.049 |
SPAG6 expression | 1.504 (1.039–2.178) | 0.031 | 1.359 (0.929–1.988) | 0.114 | 0.990 (0.575–1.705) | 0.971 |
SPAG7 expression | 0.752 (0.519–1.089) | 0.131 | 0.820 (0.560–1.202) | 0.310 | 0.854 (0.498–1.467) | 0.568 |
SPAG9 expression | 0.986 (0.683–1.423) | 0.939 | 0.906 (0.621–1.321) | 0.607 | 1.176 (0.686–2.014) | 0.556 |
SPAG10/MFGE8 expression | 0.890 (0.616–1.287) | 0.537 | 1.026 (0.703–1.498) | 0.892 | 0.696 (0.406–1.193) | 0.187 |
SPAG13/ITPRID2 expression | 0.854 (0.591–1.234) | 0.401 | 0.777 (0.532–1.134) | 0.191 | 1.170 (0.683–2.004) | 0.567 |
SPAG16 expression | 1.427 (0.985–2.069) | 0.060 | 1.257 (0.857–1.843) | 0.242 | 1.320 (0.769–2.266) | 0.314 |
SPAG17 expression | 0.936 (0.648–1.351) | 0.722 | 0.913 (0.626–1.332) | 0.637 | 0.850 (0.498–1.453) | 0.553 |