|
Sex, male/female
|
46/41
|
46/40
|
1.000
|
|
Median age, years (range)
|
57 (18–88)
|
61 (21–81)
|
0.409
|
|
Median WBC, × 109/L (range)
|
11 (0.6–297.4)
|
27.65 (0.4–223.8)
|
0.014
|
|
Median PB blasts, % (range)
|
41 (0–98)
|
36 (0–97)
|
0.544
|
|
Median BM blasts, % (range)
|
70 (32–100)
|
75 (30–98)
|
0.377
|
|
FAB classifications
| | |
0.024
|
|
M0
|
7
|
9
|
NS
|
|
M1
|
27
|
17
|
NS
|
|
M2
|
21
|
17
|
NS
|
|
M3
|
11
|
5
|
NS
|
|
M4
|
12
|
22
|
0.058
|
|
M5
|
5
|
13
|
0.050
|
|
M6
|
1
|
1
|
NS
|
|
M7
|
3
|
0
|
NS
|
|
No data
|
0
|
2
|
NS
|
|
Cytogenetics
| | |
0.006
|
|
Normal
|
36
|
44
|
NS
|
|
t(15;17)
|
10
|
5
|
NS
|
|
t(8;21)
|
7
|
0
|
0.014
|
|
inv(16)
|
8
|
2
|
NS
|
|
+8
|
1
|
7
|
0.034
|
|
del(5)
|
1
|
0
|
NS
|
|
−7/del(7)
|
4
|
3
|
NS
|
|
11q23
|
0
|
3
|
NS
|
|
Others
|
7
|
7
|
NS
|
|
Complex
|
11
|
14
|
NS
|
|
No data
|
2
|
1
|
NS
|
|
Gene mutation
| | | |
|
FLT3 (±)
|
14/73
|
35/51
|
0.000
|
|
NPM1 (±)
|
20/67
|
28/58
|
0.177
|
|
DNMT3A (±)
|
12/75
|
30/56
|
0.001
|
|
IDH2 (±)
|
10/77
|
7/79
|
0.611
|
|
IDH1 (±)
|
9/78
|
7/79
|
0.794
|
|
TET2 (±)
|
9/78
|
6/80
|
0.590
|
|
RUNX1 (±)
|
8/79
|
7/79
|
1.000
|
|
TP53 (±)
|
6/81
|
8/78
|
0.590
|
|
NRAS (±)
|
6/81
|
6/80
|
1.000
|
|
CEBPA (±)
|
6/81
|
7/79
|
0.782
|
|
WT1 (±)
|
2/85
|
8/78
|
0.057
|
|
PTPN11 (±)
|
4/83
|
4/82
|
1.000
|
|
KIT (±)
|
6/81
|
1/85
|
0.117
|
|
U2AF1 (±)
|
4/83
|
3/83
|
1.000
|
|
KRAS (±)
|
2/85
|
5/81
|
0.278
|
