Fig. 3From: Attenuated clinical and osteoclastic phenotypes of Paget’s disease of bone linked to the p.Pro392Leu/SQSTM1 mutation by a rare variant in the DOCK6 geneImpact on the osteoclastic phenotype of Paget’s disease (PDB) of the SQSTM1 and DOCK6 gene variants. Differentiation of PBMCs into mature osteoclasts (OCL) treated by RANKL and MCSF for 21 days. A Percentage of mature OCL. B Mean number of nuclei per mature OCL. C percentage of bone resorption areasBack to article page