Table 3 Analysis of the association between genetic models and aortic dissection risk
SNP | Genetic model | Genotype | OR | 95% CI | P |
|---|---|---|---|---|---|
rs145233125 | Dominant | (TC + CC)/TT | 1.042 | 0.868–1.251 | 0.647 |
Recessive | CC/(TT + TC) | 1.213 | 0.705–2.089 | 0.421 | |
Additive | TT | 1 | |||
TC | 1.018 | 0.842–1.231 | 0.850 | ||
CC | 1.216 | 0.706–2.095 | 0.415 | ||
rs11070646 | Dominant | (CG + GG)/CC | 1.109 | 0.942–1.305 | 0.192 |
Recessive | GG/(CC + CG) | 1.597 | 0.815–3.128 | 0.073 | |
Additive | CC | 1 | |||
CG | 1.069 | 0.908–1.26 | 0.405 | ||
GG | 1.620 | 0.826–3.175 | 0.062 | ||
rs201170905 | Dominant | (AG + GG)/AA | 1.183 | 1.038–1.348 | 0.011 |
Recessive | GG/(AA + AG) | 1.841 | 1.271–2.668 | 0.001 | |
Additive | AA | 1 | |||
AG | 1.078 | 0.946–1.227 | 0.253 | ||
GG | 1.900 | 1.308–2.761 | 0.001 | ||
rs1800469 | Dominant | (AG + GG)/AA | 1.203 | 1.058–1.369 | 0.010 |
Recessive | GG/(AA + AG) | 1.058 | 0.908–1.232 | 0.458 | |
Additive | AA | 1 | |||
AG | 1.209 | 1.049–1.393 | 0.013 | ||
GG | 1.193 | 1.009–1.411 | 0.038 | ||
rs900 | Dominant | (AT + TT)/AA | 0.962 | 0.762–1.215 | 0.739 |
Recessive | TT/(AA + AT) | 0.936 | 0.822–1.065 | 0.313 | |
Additive | AA | 1 | |||
AT | 0.997 | 0.778–1.277 | 0.981 | ||
TT | 0.938 | 0.738–1.191 | 0.706 |