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Fig. 5 | BMC Medical Genomics

Fig. 5

From: Differential gene expression of 3D primary human airway cultures exposed to cigarette smoke and electronic nicotine delivery system (ENDS) preparations

Fig. 5

Significantly regulated canonical pathways from WS-CM dosage compared to vehicle control. Differential canonical pathways using IPA after exposure of primary NHBE cultures to low (3.6 µg/mL Eq-Nic.), medium (7.0 µg/mL Eq-Nic.) and high (10.0 µg/mL Eq-Nic.) doses of WS-CM for A 4 or B 24 h. The values in the heatmap are the z-scores of each entity in each analysis, where orange coloring indicates a predicted activation, and blue a predicted inhibition of the entity. Dots represent entities that have insignificant z-scores (defined as < 2)

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