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Table 1 The three best-scoring terms by p-value retained as the functional description of the corresponding components in PPI network

From: GINS4 might be a novel prognostic immune-related biomarker of not only esophageal squamous cell carcinoma and other cancers

MCODE GO Description Log10(P)
MCODE_1 R-HSA-8957275 Post-translational protein phosphorylation − 12.1
MCODE_1 R-HSA-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) − 11.8
MCODE_2 GO:0032956 regulation of actin cytoskeleton organization − 5.1
MCODE_2 GO:0032970 regulation of actin filament-based process − 5
MCODE_2 GO:0007264 small GTPase mediated signal transduction − 4.7
MCODE_3 GO:0007623 circadian rhythm − 6.4
MCODE_3 GO:0048511 rhythmic process − 5.9
MCODE_4 R-HSA-168638 NOD1/2 Signaling Pathway − 8.7
MCODE_4 R-HSA-168643 Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways − 8.1
MCODE_4 GO:0032088 negative regulation of NF-kappaB transcription factor activity − 7.5
MCODE_5 hsa04350 TGF-beta signaling pathway − 7.6
MCODE_5 ko04350 TGF-beta signaling pathway − 7.6
MCODE_5 GO:0010717 regulation of epithelial to mesenchymal transition − 7.4