Table 1 The three best-scoring terms by p-value retained as the functional description of the corresponding components in PPI network
MCODE | GO | Description | Log10(P) |
|---|---|---|---|
MCODE_1 | R-HSA-8957275 | Post-translational protein phosphorylation | − 12.1 |
MCODE_1 | R-HSA-381426 | Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) | − 11.8 |
MCODE_2 | GO:0032956 | regulation of actin cytoskeleton organization | − 5.1 |
MCODE_2 | GO:0032970 | regulation of actin filament-based process | − 5 |
MCODE_2 | GO:0007264 | small GTPase mediated signal transduction | − 4.7 |
MCODE_3 | GO:0007623 | circadian rhythm | − 6.4 |
MCODE_3 | GO:0048511 | rhythmic process | − 5.9 |
MCODE_4 | R-HSA-168638 | NOD1/2 Signaling Pathway | − 8.7 |
MCODE_4 | R-HSA-168643 | Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways | − 8.1 |
MCODE_4 | GO:0032088 | negative regulation of NF-kappaB transcription factor activity | − 7.5 |
MCODE_5 | hsa04350 | TGF-beta signaling pathway | − 7.6 |
MCODE_5 | ko04350 | TGF-beta signaling pathway | − 7.6 |
MCODE_5 | GO:0010717 | regulation of epithelial to mesenchymal transition | − 7.4 |