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Table 7 The number of features left after each filtering process. miRNA–RNA pairs with MIC \(<~0.5\) both in normal samples and tumor samples were removed by MIC filtering

From: Predicting lymph node metastasis and prognosis of individual cancer patients based on miRNA-mediated RNA interactions

Cancer

#Features after

#Features after

#Features after

MIC filtering

Wilcox test

PCA

BRCA

90,837

1563

480

COAD

178,973

1969

80

HNSC

67,020

800

100

LUAD

341,146

12,981

200

LUSC

165,765

2436

200

STAD

976,763

17,445

60

THCA

38,077

3397

150

  1. The miRNA–RNA pairs with a p-value \(\ge\) 0.01 were removed by the Wilcox test. The number of features was further reduced after dimension reduction by PCA of \(\Delta\)PCCs. In both MIC filtering and the Wilcox test, each feature represents a miRNA–RNA pair, In PCA, the number of features indicates the dimension of a feature vector