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Table 4 Somatic variant interpretation catalogs by the consensus guidelines and their equivalent on CGI

From: Clinically actionable cancer somatic variants (CACSV): a tumor interpreted dataset for analytical workflows

Class

VIC/AMP–ASCO–CAP

CGI

I

Strong clinical significance

Predicted driver

II

Potential clinical significance

Predicted passenger

III

Uncertain significance

Known in

IV

Benign or likely bening

Not protein-affecting or likely neutral for oncogenesis

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BMC Medical Genomics

ISSN: 1755-8794

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