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Table 5 Computational methods evaluation in comparison to the clinically-classified subset

From: Clinically actionable cancer somatic variants (CACSV): a tumor interpreted dataset for analytical workflows

Method

Sensitivity

Specificity

NPV

Accuracy

auROC

Coverage

CACSV

1

0.6

1

0.53

0.75

1

VIC

0

0.99

0.90

0.89

0.49

0.4

CGI

0.14

0.19

0.67

0.19

0.16

0.38

  1. Negative predictive value (NPV) is the proportion of true negative to all negatives (true or false), and coverage appraise the availability of clinical annotation by the method
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BMC Medical Genomics

ISSN: 1755-8794

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