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Table 5 Computational methods evaluation in comparison to the clinically-classified subset

From: Clinically actionable cancer somatic variants (CACSV): a tumor interpreted dataset for analytical workflows

Method Sensitivity Specificity NPV Accuracy auROC Coverage
CACSV 1 0.6 1 0.53 0.75 1
VIC 0 0.99 0.90 0.89 0.49 0.4
CGI 0.14 0.19 0.67 0.19 0.16 0.38
  1. Negative predictive value (NPV) is the proportion of true negative to all negatives (true or false), and coverage appraise the availability of clinical annotation by the method