|
Characteristics1
|
Novel-1 (ICP127)
|
Novel-2 (ICP53)
|
rs180957965 (ICP12)
|
rs147030757 (ICP1)
|
rs147030757 (ICP69)
|
rs147030757 (ICP107)
|
|---|
|
Basic information1
|
|
Age (years)
|
40
|
21
|
30
|
26
|
27
|
27
|
|
Gestational age (weeks)
|
38 + 5
|
30 + 1
|
39 + 6
|
40 + 3
|
37 + 6
|
28
|
|
BMI (kg/m2)
|
28.2
|
22
|
20.4
|
25.4
|
24.6
|
22.2
|
|
Gravidity (times)
|
6
|
1
|
2
|
1
|
1
|
5
|
|
Parity (times)
|
1
|
0
|
0
|
0
|
0
|
4
|
|
Serum biochemical index
|
|
K (3.5–5.1, mmol/L)
|
4.1
|
4.3
|
4.2
|
4
|
4.2
|
3.7
|
|
Na (135–145, mmol/L)
|
137
|
142
|
143
|
135
|
140
|
140
|
|
CL (96–108, mmol/L)
|
105
|
109
|
104
|
102
|
102
|
108
|
|
Ca (2.1–2.9, mmol/L)
|
2.2
|
2.2
|
2.14
|
2.49
|
2.34
|
2.4
|
|
Mg (0.6–1.1, mmol/L)
|
0.8
|
0.91
|
0.82
|
0.74
|
0.86
|
0.7
|
|
P (0.85–1.51, mmol/L)
|
1
|
0.97
|
1.13
|
1.37
|
1.24
|
0.9
|
|
WBC (3.69–9.16, × 109/L)
|
6.45
|
7.6
|
17.59
|
7.61
|
5.81
|
5.49
|
|
RBC (3.68–5.13, × 1012/L)
|
3.8
|
3.31
|
3.99
|
3.86
|
3.8
|
3.28
|
|
PLT (101–320, × 109/L)
|
164
|
196
|
294
|
144
|
188
|
238
|
|
RDW-SD (37–54, fL)
|
51.6
|
50.4
|
44.8
|
57
|
41.5
|
43.9
|
|
ALT (0–35, U/L)
|
198
|
44
|
76
|
12
|
40
|
7
|
|
AST (0–35, U/L)
|
196
|
53
|
51
|
22
|
40
|
15
|
|
TBA (0–10, μmol/L)
|
46.4
|
113.2
|
12
|
18.9
|
27.5
|
46.4
|
|
TBIL (3.4–20.5, μmol/L)
|
31.5
|
10.1
|
14
|
13.6
|
11.9
|
9.1
|
|
DBIL (0–5, μmol/L)
|
22.4
|
7.2
|
6
|
5
|
2.5
|
4.5
|
|
IDBIL (0–14, μmol/L)
|
9.1
|
2.9
|
8
|
8.6
|
9.4
|
4.6
|
|
CHOL (0–5.2, mmol/L)
|
5.79
|
5.52
|
5.73
|
6.21
|
7.44
|
6.07
|
|
TG (0.34–1.69, mmol/L)
|
3.97
|
2.47
|
3.13
|
2.22
|
4.89
|
3.17
|
|
HDL (0.9–2, mmol/L)
|
1.59
|
1.83
|
1.6
|
2.32
|
2.29
|
2.27
|
|
LDL (0–3.74, mmol/L)
|
2.4
|
2.57
|
2.71
|
2.88
|
2.93
|
2.36
|
|
UA (155–357, μmol/L)
|
339
|
257
|
348
|
282
|
411
|
131
|
|
Outcomes of pregnancy women and newborn baby
|
|
Birth weight (kg)
|
3.8
|
–
|
3
|
3.55
|
3.85
|
–
|
|
Apgar score (1–10)
|
9
|
–
|
8
|
10
|
9
|
–
|
|
Bleeding count (mL)
|
400
|
–
|
300
|
250
|
350
|
–
|
- 1Abbreviations refer to the footnotes in Table 1
