Fig. 5
From: A systematic analysis of gene–gene interaction in multiple sclerosis
Schematic representation of the role played by the gene pairs NF-\(\kappa\)B/IP10 in the development of demyelination in MS. a Transformation of astrocytes in immuno-competent cells and T-cells recruitment following the NF-B/IP10 axis activation in MS. b After recruitment of T-cells, adhesion of T-cell/astrocyte leads to in ammatory and immune response inducing neuron damage