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Table 5 Pairs of genes identified by physical mapping, and selected because at least one of the SNPs involved has a direct consequence as protein dysfunction

From: A systematic analysis of gene–gene interaction in multiple sclerosis

Map ID

Gene pair

Type of interaction

3305

GLI-1 and SUFU

Direct interaction between the genes

Uunspecified impact on MS

4703

AKT (PKB) and MEKK1 (MAP3K1)

No direct interaction between the genes

AKT has a specified impact on MS

5611

Granzyme B and KLRK1 (NKG2D)

No direct interaction between the genes

Unspecified impact on MS

Granzyme B and PI3K cat class IA

No direct interaction between the genes

Unspecified impact on MS