Skip to main content

Table 3 Diagnostic performance of ProCAD by incorporating all chromosomes

From: Copy number variation of urine exfoliated cells by low-coverage whole genome sequencing for diagnosis of prostate adenocarcinoma: a prospective cohort study

  AUC (95% CI) Cutoff TN TP FN FP PPV (%) NPV (%) Specificity (%) Sensitivity (%) Accuracy (%)
ProCAD CHR1-22 0.91 (0.83, 0.99) 2 3 15 1 6 71.4 75.0 33.3 93.8 72.0
   2.5 9 13 3 0 100.0 75.0 100.0 81.3 88.0
   3 9 8 8 0 100.0 52.9 100.0 50.0 68.0
f/t PSA (%) 0.63 (0.42, 0.83) < 10% 7 9 7 2 81.8 50.0 77.8 56.3 64.0
   < 16% 4 11 5 5 68.8 44.4 44.4 68.8 60.0
  1. ProCAD versus f/t PSA, P = 0.012