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Fig. 4 | BMC Medical Genomics

Fig. 4

From: Integrated investigation of DNA methylation, gene expression and immune cell population revealed immune cell infiltration associated with atherosclerotic plaque formation

Fig. 4

Integrated analysis of deregulated DNA methylation, gene expression and immune cell population. (A) Venn diagram showing the overlap between DEGs and DMGs. (B) Bar plot showing cell type ratio and the number of co-expressed DEGs with DMG or without DMG. (C) Hierarchical clustering heatmap showing the correlation between enriched GO terms (biological process) and cell types for co-expressed DEGs without DMG. (D) Hierarchical clustering heatmap showing the correlation between enriched Reactome terms and cell types for co-expressed DEGs with DMG. (E) Heatmap showing the correlation pattern between expression levels of genes from extracellular matrix organization and the fractions of related immune cell types. Red color indicates positive correlation, and blue color indicates negative correlation. (F) The same with E but for the expression levels of genes from immune response and the fractions of related cell types

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