Fig. 5

Verification of genes deregulated at both expression and DNA methylation levels in atherosclerotic clinical samples. (A). Box plot showing the expression levels of 7 genes that were down-regulated in atherosclerotic PBMCs compared with those in carotid plaques samples. ***p value < 0.001, unpaired t-test. (B) The same with A but for three up-regulated genes in atherosclerotic PBMCs. (C) Bar plot showing the RT-qPCR results of 7 genes from (A) in PBMCs samples from normal individuals and atherosclerotic patients. ***p value < 0.001, unpaired t-test. (D) The same with C but for three genes from (B)