Fig. 2

Using autophagy regulators to establish risk signature ARPs in GBM. These regulators were used to create risk signatures in TCGA and GEO datasets. A Parameter selection for tuning by tenfold cross-validation in the LASSO model. B LASSO coefficient profiles of the fractions of autophagy genes. C, D ARPs measured by the time-dependent receiver–operating characteristic (ROC) curves in the training cohort (TCGA), and validation cohort (GEO). E, F KM-curve for patients with high and low ARPs in the training cohort, and validation cohort