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Table 5 Hypermethylated promoter in recurrent stone formers to cmpare gender and age

From: The correlation between promoter hypermethylation of VDR, CLDN, and CasR genes and recurrent stone formation

Gene

Female

Male

P-value

VDRa

9 (100%)

19 (90.5%)

0.483

VDRb

9 (100%)

19 (95.0%)

0.690

CLDNa

9 (100%)

14 (77.8%)

0.268

CLDNb

9 (100%)

14 (77.8%)

0.268

CasRa

8 (88.9%)

18 (94.7%)

0.575

CasRb

8 (88.9%)

18 (94.7%)

0.575

 

Age < 60

Age ≥ 60

P-value

VDRa

22 (91.7%)

6 (100%)

0.634

VDRb

22 (95.6%)

6 (100%)

0.793

CLDNa

18 (81.8%)

5 (100%)

0.561

CLDNb

18 (81.8%)

5 (100%)

0.561

CasRa

20 (90.9%)

6 (100%)

0.611

CasRb

20 (90.9%)

6 (100%)

0.611

  1. In 30 recurrent stone formers, 21 were male (70%) and 24 were under 60 (80%). Hypermethylated for each target locus are presented