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Table 1 Baseline characteristics of stage 1 and stage 2 UK Biobank cohorts

From: Exome-wide analysis of copy number variation shows association of the human leukocyte antigen region with asthma in UK Biobank

Trait Stage 1 Stage 2
Cases (N = 7098) Controls (N = 36,578) Cases (N = 17,280) Controls (N = 115,562)
Age at recruitment, years 56 (8.09) 56.9 (7.89) 55.9 (8.23) 56.7 (8.02)
Female 4199 (59.2) 19,561 (53.5) 10,197 (59.0) 63,424 (54.9)
Male 2899 (40.8) 17,017 (46.5) 7083 (41.0) 52,138 (45.1)
FEV1, % predicted 85.7 (16.6) 94.0 (14.3) 88.2 (15.3) 94.2 (14.1)
FEV1/FVC 0.733 (0.0778) 0.769 (0.0551) 0.741 (0.0709) 0.769 (0.0555)
Ever smoker 3093 (43.6) 16,055 (43.9) 7590 (43.9) 50,413 (43.6)
Never smoker 3901 (55.0) 20,002 (54.7) 9357 (54.1) 63,253 (54.7)
Unknown 104 (1.5) 521 (1.4) 333 (1.9) 1896 (1.6)
Hayfever, rhinitis or eczema status:
Yes 3483 (49.1) 8228 (22.5) 7727 (44.7) 23,269 (20.1)
No 3615 (50.9) 28,350 (77.5) 9553 (55.3) 92,293 (79.9)
  1. Data are mean (SD) or N (%), FEV1 = forced expiratory volume in 1 s, FVC = forced vital capacity