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Table 1 Baseline characteristics of stage 1 and stage 2 UK Biobank cohorts

From: Exome-wide analysis of copy number variation shows association of the human leukocyte antigen region with asthma in UK Biobank

Trait

Stage 1

Stage 2

Cases (N = 7098)

Controls (N = 36,578)

Cases (N = 17,280)

Controls (N = 115,562)

Age at recruitment, years

56 (8.09)

56.9 (7.89)

55.9 (8.23)

56.7 (8.02)

Female

4199 (59.2)

19,561 (53.5)

10,197 (59.0)

63,424 (54.9)

Male

2899 (40.8)

17,017 (46.5)

7083 (41.0)

52,138 (45.1)

FEV1, % predicted

85.7 (16.6)

94.0 (14.3)

88.2 (15.3)

94.2 (14.1)

FEV1/FVC

0.733 (0.0778)

0.769 (0.0551)

0.741 (0.0709)

0.769 (0.0555)

Ever smoker

3093 (43.6)

16,055 (43.9)

7590 (43.9)

50,413 (43.6)

Never smoker

3901 (55.0)

20,002 (54.7)

9357 (54.1)

63,253 (54.7)

Unknown

104 (1.5)

521 (1.4)

333 (1.9)

1896 (1.6)

Hayfever, rhinitis or eczema status:

Yes

3483 (49.1)

8228 (22.5)

7727 (44.7)

23,269 (20.1)

No

3615 (50.9)

28,350 (77.5)

9553 (55.3)

92,293 (79.9)

  1. Data are mean (SD) or N (%), FEV1 = forced expiratory volume in 1 s, FVC = forced vital capacity