Skip to main content
Fig. 2 | BMC Medical Genomics

Fig. 2

From: Identification of a novel CNV at the EYA4 gene in a Chinese family with autosomal dominant nonsyndromic hearing loss

Fig. 2

Identification of a novel copy number variation in the EYA4 gene in a Chinese family. a Schematic diagram showing the position of the EYA4 gene deletion on chromosome 6. The red bar indicates the alignment position of the deletion. b Copy number of each exon calculated from the fluorescence peak ratios identified from the CNV analysis. c Scheme of the normal and inverted alleles. d Gap-PCR product of the distal breakpoint junction showing segregation with the phenotype in the family. e Sanger sequencing of the inverted allele by EYA4_Ex7_F and EYA4_In11_R covering the two breakpoints and a 10-bp insertion

Back to article page