Identification of a novel CNV at the EYA4 gene in a Chinese family with autosomal dominant nonsyndromic hearing loss

Table 1 Summary of the phenotypic information of the family members

Subjects	Gender	Age (years)		Pure-tone average (dBHL)		Audiogram shape	Degree of hearing loss
Subjects	Gender	At testing	At onset	Left	Right	Audiogram shape	Degree of hearing loss
I-1	Male	76	–	82	90	–	Severe
I-2	Female	72	–	Normal	Normal	–	Normal hearing
II-1	Male	62	–	Normal	Normal	–	Normal hearing
II-2	Female	57	42	77	98	Flat	Moderate–severe
II-3	Male	54	43	83	94	Flat	Severe
II-4	Female	51	–	Normal	Normal	–	Normal hearing
II-5	Male	53	–	Normal	Normal	–	Normal hearing
II-6	Female	44	37	75	71.25	Flat–sloping	Moderate–severe
III-1	Male	32	26	55	45	Cookie–bite	Moderate
III-2	Male	30	–	Normal	Normal	–	Normal hearing
III-3	Male	27	–	Normal	Normal	–	Normal hearing
III-4	Female	26	–	Normal	Normal	–	Normal hearing
III-5	Female	26	–	Normal	Normal	–	Normal hearing
IV-1	Male	4	–	Normal	Normal	–	Normal hearing
IV-2	Female	2	–	Normal	Normal	–	Normal hearing

ISSN: 1755-8794