Fig. 2From: A novel missense variant in the CASK gene causes intellectual developmental disorder and microcephaly with pontine and cerebellar hypoplasiaBioinformatic analysis of the conservation and pathogenicity of the variant in CASK. a Multiple sequence alignment of the CASK protein for different species. The black arrow denotes the position of the variant (c.638T>G: p.L213R). b The secondary and spatial structure prediction of the WT and MUT proteinsBack to article page