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Fig. 3 | BMC Medical Genomics

Fig. 3

From: Gorham-Stout case report: a multi-omic analysis reveals recurrent fusions as new potential drivers of the disease

Fig. 3

RNA expression analysis between Gorham-Stout tissue and adjacent normal. a Volcano plot of the RNA-seq differential expression analysis showing a large number of genes up and down-regulated in GS tissue. b Results of the gene set enrichment analysis (GSEA) selecting the lymph-angiogenesis (VEGF) and osteolysis (NOTCH) pathways. A heavily weighted distribution in multiple genes was found in both pathways, with a high number of genes overexpressed in either GS tissue or the attached normal

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