Transcriptomic analysis reveals pathophysiological relationship between chronic obstructive pulmonary disease (COPD) and periodontitis

Table 3 the topological characteristic of top 20 nodes in the PPI network

Gene	Label	Degree	Average shortest path length	Betweenness centrality	Closeness centrality	Topological coefficient
SNCA	COPD&CP	249	2.424574	0.476994	0.412444	0.017938
EEF1D	COPD&CP	160	2.645985	0.303017	0.377931	0.027917
ANXA 1	COPD&CP	117	2.753041	0.222923	0.363235	0.034188
INSR	COPD&CP	114	2.753041	0.22763	0.363235	0.025146
FTH1	COPD&CP	56	2.867397	0.126682	0.348748	0.038095
NCAP D3	COPD&CP	47	2.913625	0.088015	0.343215	0.045213
CDCA 7L	COPD&CP	45	2.877129	0.122311	0.347569	0.028758
AP1S2	COPD&CP	31	2.957421	0.065846	0.338132	0.047312
FAM3 C	COPD&CP	28	2.969586	0.062619	0.336747	0.038265
UBAS H3A	COPD&CP	24	2.979319	0.041695	0.335647	0.068452
EAF2	COPD&CP	16	4.658151	0.031841	0.214677	0.083333
UBC		15	2.036496	0.322608	0.491039	0.074936
DCAF 12	COPD&CP	10	3.006083	0.017515	0.332659	0.13125
STMN 3	COPD&CP	6	3.023114	0.012136	0.330785	0.166667
NAP1L 3	COPD&CP	5	4.816302	0.009715	0.207628	0.2
EGFR		4	3.043796	0.020572	0.328537	0.261278
NRF1		4	3.50365	0.007751	0.285417	0.255981
HSPB 1		4	2.695864	0.028541	0.370939	0.273157
SQSTM 1		4	2.603406	0.029332	0.384112	0.273666
YWHA B		4	3.055961	0.022253	0.327229	0.259494

ISSN: 1755-8794