From: The effect of hemolysis on quality control metrics for noninvasive prenatal testing
Quality control metric | Hemolyzed specimen (n = 21) | Non-hemolyzed specimen (n = 21) | P |
---|---|---|---|
Library concentration (ng/μL) | 8.11 | 14.24 | < 0.001 |
Fetal fraction (%) | 20.70 | 16.18 | 0.006 |
GC content (%) | 40.68 | 40.80 | 0.162 |
Mapping rate (%) | 75.69 | 75.61 | 0.800 |
Duplication rate (%) | 12.64 | 6.84 | 0.007 |